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February 8, 2005: Magic Bullets - Drugs and their Delivery

Presentation

MagicBulletsPresentationPart1_2.pdf

Fraser Lecture, Parts 1+2, 2/8/2005

1.4 M

Readings

WonderDrugs.pdf

LeCouteur, P.; Burreson, J. Napoleon’s Buttons: 17 Molecules that Changed History; Chapter 10 “Wonder Drugs.” Tarcher: New York, 2003.

7.6 M

Where_a_Pill_Won__t_Reach.pdf

Langer, R. Where a Pill Won’t Reach” Scientific American, April 2003, 51-57.

213 K

RNAi_Therapeutics.pdf

Robinson, R. “RNAi Therapeutics” PLoS Biology 2004, Vol.2, Issue 1, 0018-0020. (PLoS Biology is a peer-reviewed, open-access journal published by the Public Library of Science, http://www.plosbiology.org)

1.5 M

 

Browse the American Cancer Society website: www.cancer.org.  Search for information about a type of cancer and select the “All about … cancer” link (e.g. breast cancer and prostate cancer may be mentioned in class.)  Browse the associated pages, paying particular attention to chemotherapy.  Also read about the history of cancer.

 

Additional Readings

Other chapters about the history of drugs in Napoleon’s Buttons:  Chapters 11-13, 17.

 

More about RNA interference:

 

RNAiCracksinArmor.pdf

Couzin, J. “RNAi Shows Cracks in its Armor” Science 2004, 306, 1124-1125.

248 K

The_RNAi_Revolution.pdf

Novina, C. D.; Sharp, P. A. “The RNAi Revolution” Nature 2004, 430, 161-164.

822 K

Speaker

Cassandra Fraser, Professor of Chemistry

Prof. Cassandra L. Fraser is an Associate Professor in the Department of Chemistry. In research, teaching, and service activities, she is especially keen on building bridges between...